Temporal changes of haematological and radiological findings of the COVID-19 infection—a review of literature

Abstract Background COVID-19 is a systemic viral infection which mainly targets the human respiratory system with many secondary clinical manifestations especially affecting hematopoietic and haemostasis. Few studies have highlighted prognostic value of blood findings such as lymphopenia, neutrophil/lymphocyte ratio, platelet/lymphocyte LDH, CRP, cardiac troponin, low-density lipoproteins chest radiographic abnormality. A study progressions radiological results may help to identify patients at high risk severe outcomes. This systematic review aimed assess temporal progression radiology COVID-19. Methods Comprehensive literature search was conducted on Medline, Embase Cochrane databases articles published for peripheral investigation patients. Results total 27 were included in this review. The common laboratory features reported include elevated levels C-reactive proteins lactate dehydrogenase. For signs, ground-glass opacifications, consolidations, crazy paving patterns frequently reported. There correlation between lymphocyte count, neutrophil count biomarkers dehydrogenase; later phase disease (more than 7 days since onset symptoms), lymphopenia worsens while protein dehydrogenase increase. Frequencies opacifications consolidations decrease that consolidation pattern rises progresses. More extensive lung involvement also seen more phases. Conclusion be helpful monitor evaluate severity.